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Corning Matrigel™ Basement Membrane Matrix

L1-6 

   

 



Corning Matrigel is especially suited for the culture of epithelial, endothelial, muscle and neuronal cells

 



Gels to form a three-dimensional model of basement membrane

 



Creates models to measure invasive potential of tumor cells

 



Corning Matrigel Basement membrane Matrix is a solubilised basement membrane preparation extracted from the Engelbreth-Holm-
Swarm (EHS) mouse sarcoma, a tumor rich in extracellular matrix proteins. Its major component is laminin, followed by collagen IV, 
entactin, and heparan sulfate proteoglycan1. It also contains TGF-ß fibroblast growthfactor, tissue plasminogen activator2, and other 
growth factors that occur naturally in the EHS tumour.

 



At room temperature, Corning Matrigel Matrix polymerises to produce a biologically active matrix material resembling the mammalian 
cellular basement membrane.

 



Corning Matrigel Basement Membrane Matrix is effective for he attachment and differentiation of both normal and transformed, 
anchorage-dependent epithelial and other cell types. It will also support in-vivo peripheral nerve regeneration and facilitates differentiation of bovine oviduct epithelial cells.

 



The Growth Factor Reduced (GFR) product is useful as an alternative to Corning Matrigel Matrix in many of the applications listed above where a more highly defined basement preparation 
is desired. It has been used to define the signals necessary in the formation of canicular cell processes in bone cells, in elucidating the role of growth factors in the formation of tubules by 
primary mouse kidney cells, and in gene expression studies of primary mouse mammary epithelial cells. The phenol red-free product is suitable for those assays that require colour detection 
(i.e. fluorescence).

 



All Corning Matrigel Basement Membrane Matrices including the High Concentration formulation can also be used to assess in-vivo angiogenic activity of different compounds by subcutaneous 
injection into mice (Corning Matrigel Plug Assay). All Corning Matrigel products are sourced from an LDEV-(Lactate dehydrogenase elevating virus) free mouse EHS tumor.

Code

Description

Qty

356234

Corning Matrigel™ Basement Membrane Matrix

5mL

354234

Corning Matrigel™ Basement Membrane Matrix

10mL

356235

Corning Matrigel™ Basement Membrane Matrix

50mL (5 x 10mL)

354248

Corning Matrigel™ Matrix High Concentration 

10mL

356237

Corning Matrigel™ Matrix, Phenol Red-free, standard concentration

10mL

354262

Corning Matrigel™ Matrix, Phenol Red-free, high concentration

10mL

356230

Growth Factor Reduced (GFR) BD Matrigel™ Matrix, standard concentration

5mL

354230

Growth Factor Reduced (GFR) BD Matrigel™ Matrix, standard concentration

10mL

354263

Growth Factor Reduced (GFR) BD Matrigel™ Matrix, high concentration

10mL

356231

Growth Factor Reduced BD Matrigel™ Matrix, Phenol Red-free

10mL

354237

Extracellular Matrix, Human Placenta

1mg

354235

Corning Dispace

100mL

354253

Corning Cell Recovery Solution

100mL

TISSUE CUL

TURE

, CORNING

TISSUE CULTURE, CORNING

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