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Corning Matrigel™ Basement Membrane Matrix
L1-6
Corning Matrigel is especially suited for the culture of epithelial, endothelial, muscle and neuronal cells
Gels to form a three-dimensional model of basement membrane
Creates models to measure invasive potential of tumor cells
Corning Matrigel Basement membrane Matrix is a solubilised basement membrane preparation extracted from the Engelbreth-Holm-
Swarm (EHS) mouse sarcoma, a tumor rich in extracellular matrix proteins. Its major component is laminin, followed by collagen IV,
entactin, and heparan sulfate proteoglycan1. It also contains TGF-ß fibroblast growthfactor, tissue plasminogen activator2, and other
growth factors that occur naturally in the EHS tumour.
At room temperature, Corning Matrigel Matrix polymerises to produce a biologically active matrix material resembling the mammalian
cellular basement membrane.
Corning Matrigel Basement Membrane Matrix is effective for he attachment and differentiation of both normal and transformed,
anchorage-dependent epithelial and other cell types. It will also support in-vivo peripheral nerve regeneration and facilitates differentiation of bovine oviduct epithelial cells.
The Growth Factor Reduced (GFR) product is useful as an alternative to Corning Matrigel Matrix in many of the applications listed above where a more highly defined basement preparation
is desired. It has been used to define the signals necessary in the formation of canicular cell processes in bone cells, in elucidating the role of growth factors in the formation of tubules by
primary mouse kidney cells, and in gene expression studies of primary mouse mammary epithelial cells. The phenol red-free product is suitable for those assays that require colour detection
(i.e. fluorescence).
All Corning Matrigel Basement Membrane Matrices including the High Concentration formulation can also be used to assess in-vivo angiogenic activity of different compounds by subcutaneous
injection into mice (Corning Matrigel Plug Assay). All Corning Matrigel products are sourced from an LDEV-(Lactate dehydrogenase elevating virus) free mouse EHS tumor.
Code
Description
Qty
356234
Corning Matrigel™ Basement Membrane Matrix
5mL
354234
Corning Matrigel™ Basement Membrane Matrix
10mL
356235
Corning Matrigel™ Basement Membrane Matrix
50mL (5 x 10mL)
354248
Corning Matrigel™ Matrix High Concentration
10mL
356237
Corning Matrigel™ Matrix, Phenol Red-free, standard concentration
10mL
354262
Corning Matrigel™ Matrix, Phenol Red-free, high concentration
10mL
356230
Growth Factor Reduced (GFR) BD Matrigel™ Matrix, standard concentration
5mL
354230
Growth Factor Reduced (GFR) BD Matrigel™ Matrix, standard concentration
10mL
354263
Growth Factor Reduced (GFR) BD Matrigel™ Matrix, high concentration
10mL
356231
Growth Factor Reduced BD Matrigel™ Matrix, Phenol Red-free
10mL
354237
Extracellular Matrix, Human Placenta
1mg
354235
Corning Dispace
100mL
354253
Corning Cell Recovery Solution
100mL
TISSUE CUL
TURE
, CORNING
TISSUE CULTURE, CORNING
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