Click here to go to the Catalogue

Scotland 01236 431 857

Export +44 (0)1482 649 665

England & Wales 0115 982 1111

Integra Bioscience Culture Flask CELLine

N1

   

The cell culture flask CELLine is a disposable bioreactor based on two-compartment technology. It allows to cultivate cells at highest densities (10

7

-10

8

 cells/ml) and to express proteins like 

monoclonal antibodies at very high concentrations.

The bioreactor CELLine is separated into a medium and a cell compartment by means of a 10 kDa semi-permeable membrane. This membrane allows a continuous diffusion of nutrients into the 
cell compartment with a concurrent removal of any inhibitory waste. The individual accessibility of the compartments allows supplying cells with fresh medium without mechanically interfering 
with the culture. Optimal oxygen supply and control of carbon dioxide levels is ensured by a silicone membrane which forms the cell compartment base.

CELLine classic (CL) is ideal for laboratory scale applications using suspension cells or adherent cells in combination with microcarriers. The unit is optimised for cultivation of hybridomas and 
many other cell types (e.g. CHO, NSO, SF cells).

CELLine adhere (AD) is specifically adapted to allow growth of anchorage-dependent cells (e.g. HEK, BHK, CHO cells). The bioreactor contains a woven, polyethylene terephtalate (PET) matrix 
in the cell compartment providing an ideal surface for cell attachement.

Technical Specifications

CELLine CL350

CELLine CL1000

CELLine AD1000

Size: L x W x H, mm

190 x 95 x 62

275 x 120 x 80 

275 x 120 x 80

Weight (g)

185

334

336

Medium compartment cap

28 mm vented (0.2 µm), green polypropylene 
cap with polypropylene liner

38 mm vented (0.2 µm), white polypropylene 
cap with polypropylene liner

38 mm vented (0.2 µm), black polypropylene 
cap with polypropylene liner

Cell compartment cap

24 mm polypropylene cap with polyethylene liner 28 mm polypropylene cap with polyethylene liner 28 mm polypropylene cap with polyethylene liner

Cell compartment inlay

None

None

PET matrix inlay

Microscopic viewing (inverted microscope) center window requires objectice working distances 

of 2.5 mm

center window requires objectice working distances 
of 2.5 mm

limited visibility due to inlay matrix

Vertical and horizontal volume markings,mL 50 - 350 

100 - 1000 

100 - 1000

Code

Description

Pack

I90010

Disposable Two-Compartment Bioreactor for suspension cells, 350mL media volume, 5mL culture volume

5

I90005

Disposable Two-Compartment Bioreactor for suspension cells, 1L media volume, 15mL culture volume

3

I90025

Disposable Two-Compartment Bioreactor with matrix inlay for anchorage-dependent cells, 1L media volume, 15mL culture volume

3

TISSUE CUL

TURE

, EQUIPMENT

TISSUE CULTURE, EQUIPMENT

954